from 575 and the base of 3639; to destroy fully (reflexively, to perish, or lose), literally or figuratively:

KJV-- destroy, die, lose, mar, perish.

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575 apo (apo');

a primary particle; "off," i.e. away (from something near), in various senses (of place, time, or relation; literal or figurative):

KJV-- (X here-) after, ago, at, because of, before, by (the space of), for (-th), from, in, (out) of, off, (up-) on (-ce), since, with. In composition (as a prefix) it usually denotes separation, departure, cessation, completion, reversal, etc.

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3639 olethros (ol'-eth-ros);

from a primary ollumi (to destroy; a prolonged form); ruin, i.e. death, punishment:

KJV-- destruction.